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Start: 8:00 am
End: 5:00 pm
Start: 8:00 am
End: 5:00 pm
Location: Hyatt Regency Cambridge, Cambridge, Massachusetts Non-coding RNAs have recently been recognized as gene-specific regulators and thus are similar in activity to a large number of protein transcription factors that are known to be critical in the transformation of cells to a malignant state. These RNAs can regulate every stage of gene expression: transcription, mRNA stability, and mRNA translation. Cancer cells have genetic and epigenetic changes from their normal counterparts and the role of non-coding RNAs in mediating these differences is beginning to emerge. These changes are a major focus of this conference. In addition, the use of short RNAs to identify novel cancer-relevant genes and to possibly treat cancer will be discussed. Start: 8:00 am
End: 5:00 pm
Location: National University Hospital, Singapore The Pathobiology of Cancer Workshop: Pathology for Early-Career Scientists will provide an intense two-day course on the molecular and morphologic aspects of human cancer for scientists working in basic cancer research. Participants will attend small group laboratory sessions taught by pathologists and study the light microscopic and gross morphologic examples of major types of adult and childhood cancers. Correlations are made with known genetic alterations in specific types of human cancer and with animal models, particularly transgenic and gene deletion mouse models. Morning and afternoon lectures will focus on the molecular mechanisms of cancer development. Following this short course, participants should be armed with the knowledge to pursue investigations that will contribute to the understanding of the etiology, prevention, diagnosis, and treatment of human cancer. | ||
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